Successful reintroduction and continuation of nivolumab in a patient with immune checkpoint inhibitor-induced bullous pemphigoid

Many advanced cancers, such as melanoma, evade the immune system by exploiting negative feedback mechanisms.Immune checkpoint inhibitor (ICI) therapy dramatically enhances immune surveillance and has revolutionized treatment of advanced melanoma.However, ICI therapy is also associated with multiple cutaneous adverse events.We describe a patient tre

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A Converse for Fault-tolerant Quantum Computation

As techniques for fault-tolerant quantum computation keep improving, it is natural to ask: what is the fundamental lower bound on space overhead? In this paper, we obtain a lower bound on the space overhead required for $epsilon$-accurate implementation of a large class of operations that Brushes includes unitary operators.For the practically relev

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AKTIVITAS KEAGAMAAN DI SITUS PURA PUSEH WASAN

The results of archaeological research at the site Puseh Wasan Temple, Sukawati, Gianyar were found the remains of a temple, ponds, statuettes, pottery and peripih box.This indicates that this site has done a religious activity.This research aims to determine the religious activities which have been done at the site of Puseh Wasan Temple.The method

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Wittgenstein and the sciences

In the Tractatus Logico-Philosophicus, Wittgenstein states that man has the ability to construct languages with which all 76% GINGER LEMON CHOC BAR meanings may be expressed, but that it is humanly impossible to immediately extract its logic from it.Thus, language is a costume that disguises thought while proposition is a figuration of reality.This

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